Agenda Details

Session Details

03:45 PM – 04:00 PM - Room 411

Large-Scale Characterization of the Location and Expansion of AAV Integrations in Macaques and Humans Following In Vivo Exposure

Kelly Martins{}, Qi Zheng{}, Zhe Zhang{}, Kanyin Olagbegi{}, Jenny A. Greig{}, James M. Wilson{} Uni...

03:45 PM – 05:30 PM - Room 411

Co-Chair

Ana Buj Bello, MD, MBA, PhD. GENETHON, EVRY, France

04:00 PM – 04:15 PM - Room 411

The Safety and Efficacy of Pre-Treatment with Imlifidase Prior to Adeno Associated Virus (AAV)-Based Gene Therapy in Non-Human Primates with Pre-Existing Anti-AAVrh74 Antibodies

Rachael Potter{1}, Sohrab Khan{1}, John Snedeker{1}, Kaitlin Adegboye{1}, Alex Haile{1}, Behnam Saya...

04:15 PM – 04:30 PM - Room 411

Bilateral Ixo-vec NHP Tolerability and Efficacy Following a Staggered Dosing Interval between Eyes - Gene Therapy nAMD

Kris Poulsen{}, Kelly Michiko Hanna{}, Diana Cepeda{}, Julio Delano Nieves{}, Ngoc D. Nguyen{}, Kris...

04:30 PM – 04:45 PM - Room 411

Monitoring Fetal and Infant Somatic Cell Genome Editing in Rhesus Monkeys with Total-Body PET

Alice F. Tarantal{1}, Michele Martinez{1}, Charles Lee{2}, Lionel Sanz{1}, Henriette O'Geen{3}, Denn...

04:45 PM – 05:00 PM - Room 411

AAV Serotype Tropism and Editing in Young Rhesus Monkeys

Alice F. Tarantal{1}, Michele Martinez{2}, Lionel Sanz{2}, Charles Lee{3}, Henriette O'Geen{4}, Arav...

05:00 PM – 05:15 PM - Room 411

The Machine Learning-Guided Fit4Function Platform Quantitatively Profiles the Biodistribution of Peptide-Modified AAV Capsids after a Single Round of Screening in Macaque

Fatma Elzahraa Eid{1}, Albert Chen{1}, Ken Chan{1}, Qin Huang{1}, Qingxia Zheng{1}, Isabelle Tobey{1...

05:15 PM – 05:30 PM - Room 411

AAV-Barcoding for High-Throughput Screening of Vector Transduction Efficiency in Cynomolgus Macaques Compared to C57BL/6 Mice

Frederick J. Ashby{1}, Samuel Anyaso-Samuel{2}, Paul D. Gamlin{3}, Nadia Kabbej{1}, Natalia Andraka{...