Agenda Details

As the toolbox and clinical applications of gene and cell therapies expand it is increasingly critical for the field to understand, predict and prevent potential immune recognition of the therapeutic vector, transgene or cell product. In this session, we will overview recent advances in our understanding of vector/transgene-related immune responses and toxicity in clinically relevant target tissues such as the eye or the brain and discuss assays that have been developed to uncover and overcome mechanisms and consequences of immune recognition of cell and gene therapy products.