Agenda Details

Learn more about sessions and presentations at the 26th Annual Meeting

Detailed Program

Predicting and Overcoming Immune Responses in Gene and Cell Therapies

As the toolbox and clinical applications of gene and cell therapies expand it is increasingly critical for the field to understand, predict and prevent potential immune recognition of the therapeutic vector, transgene or cell product. In this session, we will overview recent advances in our understanding of vector/transgene-related immune responses and toxicity in clinically relevant target tissues such as the eye or the brain and discuss assays that have been developed to uncover and overcome mechanisms and consequences of immune recognition of cell and gene therapy products.

Session Details


Abraham Scaria, PhD. AGTC (Applied Genetic Technologies Corporation), FL


Matthew R.. Gardner, PhD. Emory University, Atlanta, GA

Predicting Immune Responses and Toxicity in Ocular Gene Transfer

Kathryn L. Pepple, MD, PhD. University of Washington, Seattle, WA

Delivery of AAVs to the central nervous system using MRI-guided focused ultrasound and immunological considerations

Isabelle Aubert, PhD. Sunnybrook Research Institute/University of Toronto, ON, Canada

Assessing Transgene Immunogenicity in the Context of (LV) Gene Therapies

Andrea Annoni, PhD. SR-TIGET, Milian, Italy

Innate Immunity to AAV

Roland W Herzog, PhD. IU School of Medicine, Indianapolis, IN

This site uses cookies to offer you a better user experience and to analyze site traffic. By continuing to use this website, you accept our use of cookies.