Session Details

Session Details

01:30 PM - 03:15 PM - Ballroom 3

Francesca Vitelli - PhD - Intellia Therapeutics

Co-Chair

01:30 PM - 03:15 PM - Ballroom 3

Scott Harper - PhD - Ohio State University & Nationwide Children's Hospital

Co-Chair

01:30 PM - 01:45 PM - Ballroom 3

Pranav Mathur - DVM, PhD - Cirsium Biosciences

25: Production of Different AAV Serotypes Using a Novel Plant-Based Viral Vector Manufacturing Platform

01:45 PM - 02:00 PM - Ballroom 3

Pranali Mistry - The Ohio state University and Nationwide Children’s Hospital

26: A Novel Proviral Plasmid Reduces Cross-Packaging and ITR Promoter Activity in AAV Vector Preparations

02:00 PM - 02:15 PM - Ballroom 3

Ohnmar Khanal - PhD - Spark Therapeutics

27: Removal of Empty and Partial AAV Capsids Using Cu Ions and Oversaturated Loading on Multicolumn AEX Chromatography

02:15 PM - 02:30 PM - Ballroom 3

Xiaofei E - PhD - Solid Biosciences

28: Novel Mechanism to Increase rAAV Yield through Blocking rAAV Transduction of the Manufacturing Hek293 Cells During rAAV Production

02:30 PM - 02:45 PM - Ballroom 3

Johanna Weizenegger - Ascend

29: Enhancing Product Quality: Utilizing Salt-Tolerant Anion Exchange Chromatography in Flow-Through Mode as a Polishing Step for Advanced Process-Related Impurity Removal

02:45 PM - 03:00 PM - Ballroom 3

Thuy Linh Do - Roche

30: Optimizing Affinity Chromatography Purification for Enhanced Quality and Stability of Adeno-Associated Viral Vectors (rAAVv)

03:00 PM - 03:15 PM - Ballroom 3

Alex Meola - Oxford Biomedica (US) LLC

31: Not Created Equal: Impact of Deamidation on Capsid Heterogeneity and Anion Exchange Chromatography (AEX) Performance